Compound comparison
TB-500 vs GLP3 · Reference Compound Comparison
Comparison of two larger synthetic peptide reference standards (>30 residues) that differ markedly in backbone modification strategy.
Shared characteristics
- ·Both are synthetic peptides >30 residues in length
- ·Both lyophilized to white-to-off-white powders
- ·Both qualified at ≥99% purity by reversed-phase HPLC at 220 nm
- ·Both confirmed by mass spectrometry against theoretical [M+H]+
- ·Both ship with batch-specific COA
Side-by-side differences
| Aspect | TB-500 | GLP3 |
|---|---|---|
| Peptide length | 43 residues (acetylated) | 39 residues |
| Molecular weight | 4963.44 g/mol | 4731.4 g/mol |
| Backbone modification | N-terminal acetylation | Multiple Aib substitutions |
| Sulfur-containing residues | 1 (Met6) | None |
| Key labile site | Met sulfoxidation | Aggregation above ~5 mg/mL |
| Reconstitution | Direct in water | Mild alkalinization for ≥5 mg/mL |
When researchers choose each
TB-500 is the reference for studies on acetylated peptide fragments with methionine-driven oxidation chemistry. GLP3 is the reference for studies on Aib-stabilized longer peptides and receptor-binding analytics.
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Thymosin β-4 fragment (TB-500)
10mg vial · ≥99% purity
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GLP3 Reference Compound
20mg vial · ≥99% purity
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Research overview