BPC-157 Reference Compound Data Sheet · CAS 137525-51-0

BPC-157 is a 15-amino-acid pentadecapeptide. IUPAC peptide notation: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. CAS registry number: 137525-51-0. Also referenced in the literature as PL 14736 and Body Protection Compound 157.

Molecular formula: C62H98N16O22. Monoisotopic mass: 1418.7180 Da. Average molecular weight: 1419.55 g/mol. Calculated isoelectric point (pI): ~4.5. Net charge at physiological pH: −1.

Linear pentadecapeptide with three consecutive proline residues at positions 3-5, contributing rigid backbone geometry. Two glutamate/aspartate residues drive the slightly acidic isoelectric point. No disulfide bridges. No internal cyclization.

Each lot is qualified at ≥99% purity by reversed-phase HPLC at 220 nm (peptide bond absorption). Mass confirmation by electrospray ionization mass spectrometry (ESI-MS) against the theoretical [M+H]+ at m/z 1420.4. Endotoxin testing performed per USP <85>.

Lyophilized white-to-off-white amorphous powder. Hygroscopic. Reconstitutes readily in bacteriostatic water, sterile water for injection, or 0.9% saline. Solubility in water at 25 °C: >10 mg/mL.

Every shipment includes a batch-specific Certificate of Analysis (COA) showing identity confirmation, HPLC purity chromatogram, ESI-MS spectrum, appearance, peptide content, and endotoxin levels. COAs are archived for traceability.